Publications

Preprint    2020    2019    2018    2017    2016    2015    2014    2013    2012    2010    2009    2007    2004   

    Preprint
  • Preprint
  • 21. R. K. Garge, H. J. Cha, C. Lee, J. D. Gollihar, A. H. Kachroo, J. B. Wallingford*, E. M. Marcotte* (preprint). Antifungal benzimidazoles disrupt vasculature by targeting one of nine β-tubulins. bioRxiv.
    doi: 10.1101/2020.09.15.298828  
  • 2020
  • 2020
  • 20. R. K. Garge, J. M. Laurent, A. H. Kachroo*, E. M. Marcotte* (2020). Systematic humanization of the yeast cytoskeleton discerns functionally replaceable from divergent human genes. Genetics.
    doi: 10.1534/genetics.120.303378   pmcid: PMC7404242   bioRxiv: 10.1101/2019.12.16.878751  
  • 19. J. M. Laurent, R. K. Garge, A. I. Teufel, C. O. Wilke, A. H. Kachroo*, E. M. Marcotte* (2020). Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs. PLoS Biology.
    doi: 10.1371/journal.pbio.3000627   pmcid: PMC7259792   bioRxiv: 10.1101/668335  
  • 2019
  • 2019
  • 18. A. I. Teufel, M. M. Johnson, J. M. Laurent, A. H. Kachroo, E. M. Marcotte, C. O. Wilke* (2019). The many nuanced evolutionary consequences of duplicated genes. Molecular Biology and Evolution.
    doi: 10.1093/molbev/msy210   pmcid: PMC6409435   bioRxiv: 10.1101/366971  
  • 2018
  • 2018
  • 17. A. Akhmetov, J. M. Laurent, J. Gollihar, E. C. Gardner, R. K. Garge, A. D. Ellington, A. H. Kachroo*, E. M. Marcotte* (2018). Single-step Precision Genome Editing in Yeast Using CRISPR-Cas9. Bio-protocol.
    doi: 10.21769/BioProtoc.2765   pmcid: PMC5951413  
  • 2017
  • 2017
  • 16. A. H. Kachroo$*, J. M. Laurent$, A. Akhmetov, M. Szilagyi-Jones, C. D. McWhite, A. Zhao, E. M. Marcotte* (2017). Systematic bacterialization of yeast genes identifies a near-universally swappable pathway. eLife.
    doi: 10.7554/eLife.25093   pmcid: PMC5536947  
  • 2016
  • 2016
  • 15. J. M. Laurent, J. H. Young, A. H. Kachroo, E. M. Marcotte* (2016). Efforts to make and apply humanized yeast. Brief Funct. Genomics 348:921–925.
    doi: 10.1093/bfgp/elv041   pmcid: PMC4803062  
  • 2015
  • 2015
  • 14. A. H. Kachroo, J. M. Laurent, C. M. Yellman, A. G. Meyer, C. O. Wilke, E. M. Marcotte* (2015). Systematic humanization of yeast genes reveals conserved functions and genetic modularity. Science 348:921–925.
    doi: 10.1126/science.aaa0769   pmcid: PMC4718922  
  • 13. M. Jayaram*, C. H. Ma, A. H. Kachroo, P. A. Rowley, P. Guga, H. F. Fan, Y. Voziyanov (2015). An Overview of Tyrosine Site‐specific Recombination - From an Flp Perspective. Mobile DNA III.
    doi: 10.1128/microbiolspec.MDNA3-0021-2014   pmid: 26350308  
  • 12. Yen Ting Liu, S. Sau, C. H. Ma, A. H. Kachroo, P. A. Rowley, K. M. Chang, H. F. Fan, M. Jayaram* (2015). The Partitioning and Copy Number Control Systems of the Selfish Yeast Plasmid - An Optimized Molecular Design for Stable Persistence in Host Cells. Microbiology Spectrum.
    doi: 10.1128/microbiolspec.PLAS-0003-2013   pmcid: PMC4274994  
  • 11. B. Cannon$, A. H. Kachroo$, I. Jarmoskaite, M. Jayaram*, R. Russell* (2015). Hexapeptides that inhibit processing of branched DNA structures induce a dynamic ensemble of holliday junction conformations. Journal of Biological Chemistry.
    doi: 10.1074/jbc.M115.663930   pmcid: PMC4566245  
  • 10. P. A. Rowley$, A. H. Kachroo$, C. H. Ma, A. D. Maciaszek, P. Guga, M. Jayaram* (2015). Stereospecific suppression of active site mutants by methylphosphonate substituted substrates reveals the stereochemical course of site-specific DNA recombination. Nucleic Acids Research.
    doi: 10.1093/nar/gkv513   pmcid: PMC4499138  
  • 2014
  • 2014
  • 9. Yufeng Qian, A. H. Kachroo, C. M. Yellman, E. M. Marcotte, K. A. Johnson* (2014). Yeast cells expressing the human mitochondrial DNA polymerase reveal correlations between polymerase fidelity and human disease progression. Journal of Biological Chemistry.
    doi: 10.1074/jbc.M113.526418   pmcid: PMC3937665  
  • 2013
  • 2013
  • 8. P. A. Rowley$, A. H. Kachroo$, M. Jayaram* (2013). Selfish DNA. Brenner's Encyclopedia of Genetics.
    doi: 10.1016/B978-0-12-374984-0.01394-2  
  • 2012
  • 2012
  • 7. JN. Kalyani, Na. Ramachandra, A. H Kachroo, S. Mahadevan, H. S. Savithri* (2012). Functional analysis of the genes encoding diaminopropionate ammonia lyase in Escherichia coli and Salmonella enterica serovar Typhimurium. Journal of Bacteriology.
    doi: 10.1128/JB.01362-12   pmcid: PMC3458667  
  • 2010
  • 2010
  • 6. P. A. Rowley, A. H. Kachroo, C. H. Ma, A. D. Maciaszek, P. Guga, M. Jayaram* (2010). Electrostatic suppression allows tyrosine site-specific recombination in the absence of a conserved catalytic arginine. Journal of Biological Chemistry.
    doi: 10.1074/jbc.M110.112292   pmcid: PMC2906291  
  • 5. A. H. Kachroo, P. A. Rowley, C. H. Ma, A. D. Maciaszek, P. Guga, M. Jayaram* (2010). Restoration of catalytic functions in Cre recombinase mutants by electrostatic compensation between active site and DNA substrate. Nucleic Acids Research.
    doi: 10.1093/nar/gkq466   pmcid: PMC2965224  
  • 2009
  • 2009
  • 4. A. H Kachroo, M. Jayaram, P. A. Rowley* (2009). Metabolic engineering without plasmids. Nature Biotechnology.
    doi: 10.1038/nbt0809-729   pmid: 19668179  
  • 3. C. H. Ma, A. H Kachroo, A. Macieszak, T. Y. Chen, P. Guga, M. Jayaram* (2009). Reactions of Cre with methylphosphonate DNA - Similarities and contrasts with Flp and vaccinia topoisomerase. PLoS One.
    doi: 10.1371/journal.pone.0007248   pmcid: PMC2747268  
  • 2007
  • 2007
  • 2. A. H. Kachroo, A. K. Kancherla, NS. Singh, U. Varshney, S. Mahadevan* (2007). Mutations that alter the regulation of the chb operon of Escherichia coli allow utilization of cellobiose. Molecular Microbiology.
    doi: 10.1111/j.1365-2958.2007.05999.x   pmid: 18028317  
  • 2004
  • 2004
  • 1. A. H. Kachroo* (2004). Order in stress-Lessons from the inanimate world. Journal of Biosciences.
    doi: 10.1007/BF02712104   pmid: 15625389