This is the home page for class BIOL 367, Molecular Biology.

Syllabus

Syllabus_BIOL367_Winter2018-UPDATED 14FEB2018. Notice the changes in the Grading as well. The Discussion section grade contribution is now reduced to 10% and the mid-term exam increased to 35% contribution.

Office hours (Each Friday 3:00p-4:00p in GE110.01)

Each week Friday 3pm - 4pm in GE 110.01 seminar room at Concordia Loyola campus. Note that my office hours will be meetings as a ‘group’. If you prefer to talk to me one-one about a grade or any personal issues concerning the course, just email me and we can schedule a date for the meeting.

Discussion Group info

Check your discussion subgroup details at moodle.

EXAM DATES

Here is a list of quiz and exam dates. BIOL367 Quiz & Exam dates

8th Jan 2018

Lecture 1

General Reading (not necessary for the exams).

Reading material 1-Avery

Reading material 2-WatsonCrick

Reading material 3-Chargaff

10th Jan 2018

Lecture 2

DNA video MITxbio

General Reading (not necessary for the exams).

Arsenic bacterium

Homework Assignment and Discussion #1

Homework Assignmnet #1 Homework Assignment reading material Link 1, Link 2, Link 3, Link 4

15th Jan 2018

Lecture 3 DNA properties and Replication Pt. 1 (Chapter 2.4 and 20)

Reading material Arthur Kornberg’s famous papers. Read the main paper only for exams.

17th Jan 2018

Lecture 4

Reading material PCR

Reading material DNA sequencing

For videos go to DNA Learning Center 3D animations.

22nd Jan 2018

Lecture 5. DNA replication, repair and recombination (chapter 20)

Homework assignmnet #1 due today.

24th Jan 2018

Lecture 6. DNA replication, repair and recombination RECAP (chapter 20)

QUIZ #1 today after the lecture at HB130 (12:20p - 12:55p)

29th Jan 2018

Lecture 7. More on Replication & Recombinant DNA technology (chapter 4, 20)

Homework Assignment and Discussion #2

Homework Assignmnet #2.

Check this video at Youtube for the basic understanding of CRISPR.

(https://www.youtube.com/watch?v=6SL2eEUvycI).

31st Jan 2018

First Mid-term exam today starting at 11:55a to 12:55p at HB130. Books and notes are allowed. However, tablets, PCs, phones or any other use of internet is not allowed.

5th Feb 2018

Lecture 8. Recombinant DNA technology & Transcription (chapter 6, 7 & 10)

7th Feb 2018

Lecture 9. Prokaryotic Transcription Regulation (chapter 6 & 7)

Reading Material 1

Reading Material 2

12th Feb 2018

Homework Assignment 2 due today at 11:45am at HB130

Lecture 10. Prokaryotic Transcriptional Regulation II (chapter 6 & 7)

Reading Material 1 Lac repressor.

Reading Material 2 Lambda repressor.

Reading Material 3 A tale of two repressors.

14th Feb 2018

Quiz#2 today at 12:15am at HB130

Problem set to discuss today instead of the lecture (11:45 - 12:15 am at HB 130).

Proboem Set BIOL367

28th Feb 2018

Lecture 11. Prokarytic and Eukaryotic transcription (Chapter 6,7,10, 11).

5th Mar 2018

Lecture 12. Eukaryotic transcription (Chapter 10, 11, 13).

Reading Material 1 Transcription regulation.

Reading Material 2 Chip-Seq.

7th Mar 2018

Homework Assignment and Discussion #3

Homework Assignmnet #3.

Homework Assignment #3 reading material, Link 1, Link 2.

Lecture 13. RNA Splicing and Transcription factors (Chapter 14, 11).

12th Mar 2018

Lecture 14. RNA Splicing and Transcription reporters (Chapter 14, 12).

14th Mar 2018

Lecture 15. RNA editing and RNA interference (Chapter 16).

Reading material for Lecture 15. Link 1 - RNA editing 1, Link 2 - RNA editing 2, Link 3 - RNA editing 3, Link 4 - RNAi 1, Link 5 - RNAi 2, Link 6 - RNAi Nobel, Link 7 - Other regulatory RNAs, Link 8 - The human genome.

19th Mar 2018

Quiz#3 today at 11:55 am at HB130

21st Mar 2018

Lecture 16. Translation (Chapter 17, 18, 19).

26th Mar 2018

Lecture 17. Translation (Chapter 17, 18, 19).

Homework Assignment #3 due today at 11:45am

28th Mar 2018

Lecture 18. Translation (Chapter 17, 18, 19).

Grading BIOL 367_For upload_April9th 2018.pdf

9th April 2018

RECAP & discuss grades.

11th April 2018

RECAP Lecture 1-3.pdf.

Books

Book 1: The Eighth Day of Creation: Makers of the Revolution in Biology for historical perspective.

Book 2: Molecular Biology by Robert F. Weaver is an official textbook for the class.

Book 3: Molecular Biology of the Gene alternate text book.