The Evolution of the Human Genome

Human Genome Project investigators aim to create tools that assist them in pinpointing specific genes. These include the genetic map, which displays landmarks more or less evenly spaced along chromosomes; and physical maps consisting of sets of DNA that span entire chromosomes. Evolutionary Changes As mutations accumulate in human eggs and sperm cells, they occasionally…

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Humanization of yeast genes with multiple human orthologs

Humanization of yeast genes with multiple human orthologs

We published two articles focusing on the replaceability of yeast genes with their human equivalents, particularly the duplicated human genes. Summary of the Cover “Cytoskeleton genes are responsible for forming the structural (architectural) components of cells and have expanded into multigene families in humans relative to earlier ancestors. In this issue, Garge and colleagues studied the…

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